General Hospital appears set for a packed week with several major developments, particularly for characters like Lulu Spencer and Rocco Falconeri. The spoiler video for the week offers glimpses into multiple plotlines and suggests that it will be an intense week for the soap opera.

Here is a breakdown of what fans can expect from General Hospital in the coming week.

General Hospital preview shows spoilers from May 18-22
The preview video for General Hospital for the week of May 18 to May 22, 2026, features several major developments across the soap opera.
The video begins with Lulu attempting to explain to Dante Falconeri why she has passports and packed bags for herself and their son, Rocco. Now that Dante knows Rocco shot WSB director Cullum, he appears determined to help his son avoid trouble. Dante tells Lulu, “You will make my son a fugitive over my dead body.”
It is unclear what will happen when Rocco finds out about the fake identity and Lulu’s escape plan. The teaser does not provide any indication regarding that development.
Meanwhile, Josslyn Jacks explores the cell where she was locked up. She discovers that someone else had been held captive there before her. “Anna Devane was held captive here,” a note reads on the wall. “I was taken on 10-31-25.” She finds the message after moving the bed. It seemingly gives her more motivation to escape. “I got myself into this room,” Josslyn declares, “and I’m gonna get myself out.”
A glimpse of her escape plan reveals that she hits someone with a chair.
Elsewhere, Nina Reeves injected Jack Brennan with the same drug that Willow Tait has been using to keep Drew Cain unconscious. She now appears determined to keep Jack in that condition. In the teaser, Nina can be seen preparing to inject another dose into his IV at the hospital. However, Jack shows a slight twitch, indicating that he may be close to regaining consciousness.
So, there is a lot waiting for fans this week on General Hospital. New episodes air Monday through Friday on ABC.

